University of Missouri-Kansas City, Spencer Building, 5009 Rockhill Rd., Kansas City, MO 64110
2023
Nikonova E., Canela Grimau M., Barz C., Esser A., Bouterwek J., Roy A., Gensler H., Hess M., Straub T., Forne I., Spletter M.L.. 2023 [preprint]. Bruno 1 regulates cytoskeleton dynamics and a temporal splicing transition to promote myofibril assembly, growth and maturation in Drosophila flight muscle. bioRxiv. https://www.biorxiv.org/content/10.1101/2023.06.24.546382v1
Zhang X., Avellaneda J., Spletter M.L., Lemke S., Mangeol P., Habermann B.H., Schnorrer F. 2023 [preprint]. A mechanically regulated liquid-liquid phase separation of the transcriptional regulator Tono instructs muscle development. bioRxiv.
2023
Borozan L., Royas Ringeling F., Kao S.-Y., Nikonova E., Monteagudo-Mesas P., Matijevic D., Spletter M.L.*, Canzar S.*. 2023. Counting pseudoalignments to novel splicing events. Bioinformatics: 39(7). btad419. https://doi.org/10.1093/bioinformatics/btad419
2022
Ringeling F.R., Chakraborty S., Vissers C., Reiman D., Patel A.M., Lee K.H., Hong A., Park C.W., Reska T., Gagneur J., Chang H., Spletter M., Yoon K.J., Ming G.L., Song H., Canzar S. 2022. Partitioning RNAs by length improves transcriptome reconstruction from short-read RNA-seq data. Nat Biotechnol. https://doi.org/10.1038/s41587-021-01136-7
Nikonova E.*, Mukherjee A.*, Kamble K.*, Barz C., Nongthomba U., Spletter M.L. 2022. Rbfox1 is required for myofibril development and maintaining fiber-type specific isoform expression in Drosophila muscles. Life Sci Alliance: (5)4: e202101342. https://doi.org/10.26508/lsa.202101342
2021
Kao S.Y.*, Nikonova E.*, Chaabane S., Sabani A., Martitz A., Wittner A., Heemken J., Straub T., Spletter M.L. 2021. A candidate RNAi screen reveals diverse RNA-binding protein phenotypes in Drosophila flight muscle. Cells. 10: 2505.
https://doi.org/10.3390/cells10102505
2020
Nikonova E.*, Kao S.-Y.*, Spletter M.L. 2020. Contributions of alternative splicing to muscle type development and function. Semin Cell Dev Biol. Feb 15. pii: S1084-9521(19)30126-0. https://doi.org/10.1016/j.semcdb.2020.02.003
2019
Kao, S. Y.*, Nikonova, E.*, Ravichandran, K.*, Spletter, M. L. Dissection of Drosophila melanogaster Flight Muscles for Omics Approaches. J. Vis. Exp. (152), e60309, doi:10.3791/60309 (2019).
Nikonova E.*, Kao S.-Y.*, Ravichandran K., Wittner A., Spletter M.L. 2019. Conserved functions of RNA-binding proteins in muscle. Int J Biochem Cell Biol. 110: 29-49.
DOI: 10.1016/j.biocel.2019.02.008
2018
Spletter M.L., Barz C., Yeroslaviz A., Zhang X., Lemke B., Bonnard A., Brunner E., Cardone G., Basler K., Habermann B.H., Schnorrer F. 2018. A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle. Elife. 7:e34058.
DOI: 10.7554/eLife.34058
Loison O.*, Weitkunat M.*, Kaya-Copur A., Nascimento Alves C., Matzat T., Spletter M.L., Luschnig S., Brasselet S., Lenne P., Schnorrer F. 2018. Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation. PLoS Biology. 16(4):e2004718.
DOI: 10.1371/journal.pbio.2004718
2015
Spletter M.L., Barz C., Yeroslaviz A., Schönbauer C., Ferreira I.R., Sarov M., Gerlach D., Stark A., Habermann B.H., Schnorrer F. 2015. The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle. EMBO Rep. 16 (2): 178-91.
2014
Cao J., Ni J., Ma W., Shiu V., Milla L.A., Park S., Spletter M.L., Tang S., Zhang J., Wei X., Kim S.K., Scott M.P. 2014. Insight into insulin secretion from transcriptome and genetic analysis of insulin-producing cells of Drosophila. Genetics 197 (1): 175-92.
DOI: 10.1534/genetics.113.160663
Spletter M.L., Schnorrer F. 2014. Transcriptional regulation and alternative splicing cooperate in muscle fiber-type specification in flies and mammals. Exp Cell Res 321 (1): 90-8.
DOI: 10.1016/j.yexcr.2013.10.007
2012
Chen S., Spletter M.L., Ni X., White K.P., Luo L., Long M. 2012. Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila. Cell Rep 1 (2): 118-32.
DOI: 10.1016/j.celrep.2011.12.010
2010
Chou* Y.H., Spletter* M.L., Yaksi* E., Leong J.C.S., Wilson R.I., Luo L. 2010. Diversity and wiring variability of olfactory local interneurons in the Drosophila antennal lobe. Nature Neuroscience 13 (4): 439-49.
DOI: 10.1038/nn.2489
Li L., Tasic B., Micheva K.D., Ivanov V.M., Spletter M.L., Smith S.J., Luo L. 2010. Visualizing the distribution of synapses from individual neurons in the mouse brain. PLoS ONE 5 (7): e11503.
DOI: 10.1371/journal.pone.0011503
pre-2010
Spletter M.L., Luo L. 2009. A new family of odorant receptors in Drosophila. Cell 136 (1): 23-5.
DOI: 10.1016/j.cell.2008.12.031
Spletter M.L., Liu J., Liu J., Su H., Giniger E., Komiyama T., Quake S., Luo L. 2007. Lola regulates Drosophila olfactory projection neuron identity and targeting specificity. Neural Development 2: 14.
Li J., Spletter M.L., Johnson J.A. 2005. Dissecting tBHQ induced ARE-driven gene expression through long and short oligonucleotide arrays. Physiol Genomics 21: 43-58.
DOI: 10.1152/physiolgenomics.00214.2004
Li J., Spletter M.L., Johnson D.A., Wright L.S., Svendsen C.N., Johnson J.A. 2005. Rotenone-induced caspase 9/3-independent and –dependent cell death in undifferentiated and differentiated human neural stem cells. J Neurochem 92: 462-76.
DOI: 10.1111/j.1471-4159.2004.02872.x
Spletter M.L. 2005. Photosynthesis in A. thaliana cotyledons with random, ordered and clustered stomata. In Yingst R.A., Brandt S.D., Rudd M., Borg J., Roethel A. (Eds.) 12th Annual Conference Space Ventures and 13th Annual Conference Our Changing Earth (pp. 45-53). University of Wisconsin-Green Bay: Wisconsin Space Grant Consortium.
IFM, TDT, leg, Bru1/Aret-IR IFM
from Spletter et al., EMBO Rep, 2015
8 timepoints of IFM development, salmIR and salm mutant IFM
from Spletter er al., Elife, 2018
IFM developmental timecourse read count data visualized as UCSC genome browser tracks
from Spletter er al., Elife, 2018
Transcriptome changes in Bru1/Aret-IR and Salm-IR IFM; UCSC genome browser tracks of read count data
from Spletter er al., Elife, 2018
Developmental leg datasets, updated mapping of IFM and mutant datasets
from Kao et al., J Vis Exp, 2019
control, SF1-IR and Hrb87F-IR IFM at 72 h APF
from Kao et al., Cells, 2021
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